I ran into some problems loading up recently as well. I was able to get things running again after these steps:
Closed everything down.
Deleted eqclient.ini from Everquest directory (this is a pain without backups but ~
)
Set permissions and compatibility modes to the following:
eqgame.exe - Run as administrator, run in compatibility mode (Windows XP Service Pack 3)
MQ2 - Doesn't run as admin, no compatibility mode
WinEQ2 - Run as admin, compatibility mode XP S.P.3
EQBCS - Doesn't run as admin, no compatibility mode
I apply those settings to all corresponding shortcuts as well, not sure that makes any difference.
Ran OptionsEditor.exe
Restarted a couple times, and it ran just like normal.
I'm not sure how User Account Control (UAC) settings might affect things. I keep UAC at the lowest possible setting though, never notify.